![]() ![]() Again, this is done predominantly on Ethereum – many applications use the ERC-20 token standard. The most common practice, however, is to issue tokens on a smart-contract-capable chain. ![]() Once the new chain is live, holders can swap their tokens for fresh ones issued on top of it. In this case, users can buy tokens that are sent to their addresses on the chain.Īlternatively, the blockchain might not have launched, in which case the tokens will be issued on an established one (such as Ethereum). Sometimes, the team hosting it will have a functional blockchain that they’ll continue to develop in the coming months and years. The issuer registers their offering as a securities offering with the relevant government body, which subjects them to the same treatment as traditional securities.Īn ICO can take many forms. Also, this could help them steer clear of any uncertainty. Some companies decide to take the STO route as a way to offer equity in the form of tokens. As a result, the industry has yet to see any meaningful regulation. On the legal side, however, they’re completely different.ĭue to some legal ambiguity, there is no consensus on how regulators should qualify ICOs (discussed in more detail below). Security Token Offerings were once branded the “new ICOs.” From a technological standpoint, they’re identical – tokens are created and distributed in the same manner. The team behind the IEO benefits from increased exposure, and the exchange stands to gain from the project’s success. When a reputable exchange supports an IEO, users can expect the project to have been rigorously audited. This can be beneficial to all parties involved. The exchange partners with the team to allow its users to buy tokens directly on its platform. The key difference is that an IEO is not hosted solely by the project’s team, but alongside a cryptocurrency exchange. Initial Coin Offerings and Initial Exchange Offerings are similar in many ways. Alternatively, they might host an ICO to include a broader range of investors and raise capital for a new blockchain-based product. In this case, a business already has a product or service and issues a token to decentralize its ecosystem. Established enterprises sometimes choose to launch a reverse ICO, which is functionally very similar to a regular ICO. The practice isn’t just used by new startups, though. ![]() What’s more, a lack of cryptocurrency regulation deters many from considering blockchain startups. In the blockchain space, established firms rarely invest in projects on the merits of a white paper. Often, new entrants struggle to secure capital without an already functional product. ICOs can be a viable alternative to traditional funding for tech startups. When ICO investors purchase tokens, they are not buying any ownership in the company. In contrast, ICOs are used as a fundraising mechanism that allows companies to raise funds for their project in very early stages. IPOs usually apply to established businesses that sell partial ownership shares in their company as a way to raise funds. While the name sounds similar to an Initial Public Offering (IPO), the two are fundamentally very different methods of acquiring funding. Since then, it has been adopted by hundreds of ventures (particularly during the 2017 boom), with varying degrees of success. The practice was popularized in 2014 when it was used to fund the development of Ethereum. ![]()
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![]() ![]() VR support has been in the game for several years now, and it continues to improve with every update. I’m a huge VR helicopter simulation enthusiast and have almost all of the helicopter models on offer, as well as a handful of planes. One big negative of DCS World is the lack of proper VR controller support, which can sometimes leave you fumbling for your keyboard to find some of the controls, but don’t let this put you off from an otherwise massively impressive VR flight simulator. It comes with one map and two planes to try, but additional maps and aircraft must be purchased separately.ĭCS World has a significant learning curve, and just mastering one aircraft will take many, many hours of practice. The base game is free to download from the DCS website (recommended), but you can also get it on Steam, and it is compatible with most PC VR headsets. There are currently 7 large, details maps ranging from Nevada to the Persian Gulf, providing plenty of variety in the scenery, and a large selection of planes and helicopters ranging from WW2-era up to modern aircraft still in service today. Whilst Microsoft Flight Simulator is my favorite VR flight simulator for civilian planes, DCS World is far superior when it comes to military VR flight simulation and VR helicopter simulation. The attention to detail in each aircraft and the accuracy of the flight models are astonishing, and the graphics and sound combine to create an ultra-realistic VR flight simulator. DCS WorldĭCS World is a combat flight simulator developed by Eagle Dynamics that allows you to fly a wide range of military planes and helicopters that are meticulously modeled to be as close to their real-life counterparts as possible. You will need a powerful computer to run Microsoft Flight Simulator VR at a decent frame rate, but if your computer is up to the task, this is a fantastic option. Overall, Microsoft Flight Simulator is an incredible game, raising the bar for VR Flight Simulators in almost every way. There is also a thriving in-game marketplace where you can purchase additional planes, airports, liveries, and more, although the cost of these will soon mount up if you want to make a lot of purchases. The range of planes available to fly in the Game Of The Year edition is quite reasonable, so you can try flying an Airbus A320, Boeing 747, F/A-18 Super Hornet, a Cessna 152, or anything in between. If you want to use a gamepad to fly a plane with arcade-style controls, you can do this with ease, but if you are a hardcore flight sim enthusiast, you are also extremely well-catered for. What I particularly love about this version of Microsoft Flight Simulator is that it caters to the entire range of players. VR controller support is still average at best, and there is no support for hand tracking, which would be a fantastic addition to have in a future update. ![]() The VR implementation isn’t without bugs, but I have seen things improve steadily since it was initially released. I absolutely love tinkering around with the different weather settings, challenging myself to make difficult landings in adverse weather conditions, or picking a clear, sunny day to enjoy the sights of some incredible landmarks and cities. ![]() ![]() You can completely customize the weather and choose what time of day to fly at, creating conditions that are as challenging as you like. Microsoft Flight Simulator has now implemented full VR support, which works well on every headset I have tried it with, although you are highly likely to need to turn down some graphics settings to keep the framerate at a playable level. It uses real-world map data, photogrammetry, and satellite imagery to allow you to fly anywhere in the world, and the number of hand-crafted airports, aircraft, and landmarks continues to increase with every update. It is visually stunning, and the attention to detail in the planes, flight models, and the scenery is incredible. The most recent edition of Microsoft Flight Simulator was released in 2020 by Asobo Studio and is one of the most impressive flight simulators I have ever played. Microsoft Flight Simulator (Credit: Asobo Studio) ![]() ![]() ![]() She gives him some pointers and before you know it, they're out line dancing together, where they run into Zogu himself! As Reed realizes that he's foolishly put the lives of everyone at the school in danger, the clock starts ticking and the race to get the flash drive is on. Thankfully for him, there's Olivia (Darla Taylor), the hot teacher who handles the other kindergarten class. At any rate, he somehow convinces the woman who runs this progressive, highly priced private school, Miss Sinclaire (Sarah Strange), that he's the right man for the job and before you know it, he's being peed on by kids and letting peanuts into the classroom. Zogu will go to jail and everyone will be happy. He'll go undercover as the dead teacher's replacement, find the flash drive with the important information on it, and seal the deal. It's here that Reed, who lives in a trailer with a weight set on his front lawn, comes up with his genius plan. ![]() But in order to solidify their case against Zogu, they need to find a flash drive that belonged to a kindergarten teacher who has since gone the way of the dinosaur. Along the way, Reed got too close - he fell for Zogu's hot blonde mistress, Katja (Rebecca Olson). When Reed isn't pimping for Twix, he's catching bad guys, bad guys like an Eastern European mobster named Zogu (Aleks Paunovic). He plays by his own rules but has a decent relationship with his partner, Sanders (Bill Bellamy) even if their commanding officer frequently rakes them over the coals. agent named Reed who lives in a Seattle that's actually Vancouver. Lundgren doesn't play a cop, he plays an F.B.I. So it would stand to reason that if you were going to make a straight to video sequel to Kindergarten Cop, you'd get him to direct, right? And that's what happened, but this time out, there's no Arnold Schwarzenegger, there is instead Dolph Lundgren.Īdditionally, there is no cop. A quick look at his filmography shows that he has been behind follows up to Lake Placid, Jarhead, Sniper and Tremors. ![]() Cast: Dolph Lundgren, Bill Bellamy, Darla Taylor, Sarah Strange, Aleks Paunovicĭirector Don Michael Paul seems to have a bit of a cottage industry firmly in his grasp, in that he directs straight to video sequels to popular films. ![]() ![]() ![]() That can be a time-consuming process when you don’t have a single source of truth to pull from. The more people you contact and have a conversation with, the likelier you will hit your sales goals.īut each time you contact a new person, you need to pull up information about your last conversation and figure out what needs to be said. Sometimes, being a successful salesperson is a numbers game. They give you a simple way to analyze your performance objectively. Sales tracking templates can help you fix this. Weaknesses can fly under the radar and impact your performance without you realizing it. When used correctly, they can help you achieve the following key sales goals: Identify weaknessesĮven if you strive to be 100% honest with yourself about your performance at work, it’s not always easy to do. Sales tracking templates are much more than a simple document you add data to. Using a sales tracking template can help you accomplish these goals People use sales tracking spreadsheets because they help them keep tabs on how they’re progressing with their sales efforts on a day-by-day basis. It can be challenging to do this without a dedicated tool, which is exactly what daily sales forecasting templates offer. People use daily sales forecasting templates to make it easier to maintain a high-level view of future sales expectations. The specific ways a sales tracking template supports a salesperson will vary based on the template’s purpose. Daily sales goal tracking templates also help salespeople keep on pace to hit their overall goals with daily sales data. There are multiple types of templates, which track different aspects of the sales cycle.ĭaily sales forecasting templates help salespeople forecast their future sales more accurately by updating with daily data. Understanding daily sales tracking templatesĪ daily sales tracking template is a spreadsheet that a salesperson uses to track some aspect of their daily sales process. Read on to see our picks for the top daily sales tracking templates of 2021. We’ve put together this article to help you get started with daily sales tracking templates. Having access to this data could be just what you need to continue improving and beat out the competition. ![]() These spreadsheets help salespeople keep track of their daily performance and provide insight into various aspects of the sales process. That’s what makes daily sales tracking templates such a good tool for salespeople. Embracing this mindset is key to reaching your goals in sales. In situations like these, it’s important to take advantage of every opportunity you have to get better. Those in the industry often need to outperform their competitors to be successful. To perhaps state the obvious, sales is a competitive industry. Now we’re outlining strategies you can use to get as much out of your daily sales tracking templates as possible. In our original article, we highlighted some of the best daily sales tracking templates for startups. ![]() ![]() ![]() Locate apps that are consuming more resources and right-click o it to End Task them.Press Ctrl + Shift + Esc to open Task Manager.You need to close all those programs that are not required. It is because multiple programs use more resources leaving less for games. If you are running the Ring of Elysium with multiple applications you are prone to see the crashing or stuttering issues. Once it finishes playing the game to see if the crashing or launching problem is resolved. Click on thr Local Files and choose Verify Integrity Of Game Files.Right-click on thre Ring of Elysium and choose Properties.During this process, Steam will scan the missing files and replace them with new ones. To fix it you need to check the integrity of game files using the Steam launcher. The Ring of Elysium crashing on startup error is showing up because there might be game files that got corrupted or missing. To fix this issue you need to install the game patch from their official site and then play the game. If you didn’t have installed the game patch the Ring of Elysium will crash on startup or even show you a black screen. The developers of the Ring of Elysium regularly release new updates/game patches that fix bugs and performance-related issues. On the other hand, if you want to update a driver a go then buy Driver Easy’s Pro version which comes with customer support and a 30-days money-back guarantee. If you download the Free version then it will scan and update the driver one by one. The Driver Easy has a Free and Paid version to download on PC. This tool automatically scans and update all the outdated driver helping you play games seamlessly. If you are a newbie then we recommend you to download Driver Easy which is the No.1 PC driver updater software. to do that you are required to have computer skills and patience. In the Manual method, you will have to visit the AMD/NVIDIA sites and locate the compatible driver to install it. It’s important that you have the latest graphics driver on your PC, for that there are two methods Manual and Automatic. Make sure that you are playing games with the latest graphics driver. One of the most common causes that cause Rings on Elysium crashes is the outdated graphics driver. These tools interfere in the proper execution of games because they consider some game files as threats.Įither disable them running in the background or simply uninstall them from your PC. You will face a Ring of Elysium crashing error if you have installed the antivirus software on your PC. ![]() try not to change to FULLSCREEN, If you did it will start crashing again. This will open your game in Windowed Mode and once in you can change to Borderless.
![]() Most reactions to common food allergens - peanuts or shellfish, for example - happen within minutes after you are exposed to them. The symptoms of an alpha-gal allergic reaction usually take longer to start compared with those of other food allergies. Check your whole body for ticks after you spend time outside. Wear long pants and long-sleeved shirts when you're in wooded, grassy areas. If you have a serious allergic reaction, you may need medicine called epinephrine and treatment at the emergency room.Īvoid tick bites to prevent alpha-gal syndrome. There's no treatment other than avoiding red meat and other products made from mammals. Researchers think that some of these people may be affected by alpha-gal syndrome. Tests also show that they don't have other food allergies. There are people who often have serious allergic reactions, also called anaphylactic reactions, for no clear reason. Some people may have alpha-gal syndrome and not know it. ![]() Alpha-gal syndrome has been diagnosed in parts of Europe, Australia, Asia, South Africa, and South and Central America. Other types of ticks carry alpha-gal molecules in different parts of the world. Deer are carrying the Lone Star tick to new parts of the country. But the condition appears to be spreading farther north and west. Most cases of alpha-gal syndrome are reported in the south, east and central United States. The authoritative record of NPR’s programming is the audio record.The Lone Star tick is found mainly in the southeastern United States. ![]() This text may not be in its final form and may be updated or revised in the future. NPR transcripts are created on a rush deadline by an NPR contractor. Visit our website terms of use and permissions pages at for further information. You can probably see some of her TikTok videos, I imagine, somewhere on the Internet. MARTIN: Taylor Lorenz, a staff writer for The Atlantic. And they could continue to spend a billion dollars every year and be fine. So, you know, spent a billion - they spent a billion dollars in marketing alone last year, you know, getting people to download the app, promoting it to American users. ByteDance just - as you mentioned, one of the most valuable startups in the world - is pouring tons of money into this. I mean, again TikTok's popularity is only rising. MARTIN: How much of that has to do with the company that started this, the tech startup ByteDance, which is the most valuable tech startup in the world? I mean, is that going to give TikTok more staying power, do you think, in the long term? I mean, you'll see this even evident in terms of, like, the videos that go viral. And, you know, I feel like it kind of just continues to grow. But in the past six months, it's really exploded. And it kind of - I would say it, like, was under the radar. And then ByteDance, which owns TikTok, launched in the U.S. It had already been launched internationally and was kind of huge in Southeast Asia, India, all over the world. If anything, it seems to continue to be growing. LORENZ: How is the popularity fading? I don't think - I would kind of push back on that. MARTIN: What does that mean that in the course of a year, TikTok got so popular, and now popularity is already now fading? MARTIN: I mean, one year in regular life is like seven years in Internet life or something like that. I mean, people spending their dollars there are getting more impact than spending them even on Instagram and Facebook. It's still emerging in the advertising space. Chipotle actually did a massive campaign with YouTuber David Dobrik. MARTIN: And it's attracted corporate America, right? I mean, major brands have started using TikTok. I think the ability to add kind of any sound inspires creativity and sort of - it's just fun. And you can't make them as entertaining to watch, I guess. But you can't really share them as easily. I mean, yeah, you can make short videos on other platforms. What makes this one special, and what's been the impact of it? MARTIN: So we can make short videos on other platforms. ![]() It had a lot of fun video-editing techniques. That could be music or a voiceover or anything. It allows you to record videos as long as 15 seconds to a minute but to - down. LORENZ: TikTok is a short-form video app. MARTIN: So before we talk about what is hot being less so, explain how TikTok works. Taylor Lorenz covers technology for The Atlantic. And now, as if on cue, its popularity is in decline. And if it seems like tick tock showed up on our phones 15 seconds ago, you might be shocked to learn that the app is now an entire year old. Have you heard of TikTok? This is the social media app that lets users create super-short videos and then loop them. ![]() ![]() ![]() Step 2After that, click the Convert to prompt the online converter to start the conversion process. Then, on the main interface of the website, click the Select File then choose the way you want to add them either From My Computer, By URL, From Google Drive, and From Dropbox and From One Drive. Steps to Convert WebM to GIF with CloudConvert: What makes it distinct from other converters available online is that it has additive options that allow you to modify the resolution, codec, aspect ratio, and FPS that you can use before importing your file. Similarly, it supports tons of input and output formats. It supports options to control video resolution, quality, and file size. CloudConvertĬloudConvert is an online tool that is able to convert files into other formats. Step 4Lastly, click the Download button to finally save your GIF file. Step 3After that, click the Convert button then wait for the file to fully upload, the process will take some time so you should wait for the converting process to finish. Make sure that the converter is selected on WebM to GIF. Step 2Then, add your WebM file by clicking the Choose Files, From Dropbox, and From Google Drive. Step 1Go to or on your browser just simply search Convertio WEBM to GIF Converter. Steps to Convert WebM to GIF with Convertio: Like the usual converter that is available online, it supports various input and output formats but requires an internet connection in order to perform the conversion process. Step 4Lastly, click the Convert Now button to start the conversion process and save it on your device.Ĭonvertio is simply a converter that can convert your WebM files to gif online & for free. Step 3Then, simply click the Convert To button then on the drop-down menu select GIF as the output file format. On the main interface, click the Add Files button to add your WebM file. Step 2After that, it will direct you to the main webpage where to do the conversion task. Step 1On your device browser, go to to access the full functionality of the online tool. Similarly, it is limited in some functions like file size input and formats and like the other online tool, it requires internet connection. Zamzar is a free online file converter that is capable of converting files to a variety of formats. After that, save the GIF on your computer. Step 4Lastly, click the Convert button to start converting your WebM into GIF. Step 3On the Video to GIF Converter tool, click the Choose File button to manually add your WebM or paste a video URL of the WebM file then click the Upload Video button. ![]() Step 2On the website main interface, choose Video to GIF and it will direct you to the tool where to convert your WebM to GIF. Step 1Go to to access the online tool and make sure to have a stable internet connection. Similar to other online tools, it requires an internet connection to perform the converting process. Aside from that, it also supports additive tools that allows you to improve your file before saving them. It features a simple online GIF maker and toolset for basic animated GIF editing which allow you to create, resize, crop, reverse, optimize, and apply some effects to GIFs. EZGIFĮZGIF is an online converter tool that is primarily designed for converting files. With that, below are the selected online converters together with their simplified steps on how to WebM to GIF. If you want to easily produce GIF files out of your WebM files without having to download or install any additive tools or software, then an online converter is fit for what you are looking for. On macOS, use Adobe image viewers and editors, including Adobe Illustrator.Free Download Free Download Learn more 2. On Windows, open GIFs with Microsoft Photos, Adobe Photoshop Elements, Roxio Creator NXT Pro, and others. To open a GIF for the purposes of editing it, use an application such as Adobe Photoshop. GIFs open easily on almost all image-viewer applications, web browsers, and operating systems. Furthermore, GIF opens on Apple’s mobile devices, including iPhone and iPad, which makes it more popular than Adobe Flash. How to open a GIF file?Īlmost all web browsers support GIF, which gives it a distinct advantage over other image formats, such as PNG. The most common use of GIF is in animated form as advertisements, emotion-based replies on social media, and memes, which often go viral on the Internet. Unlike the uncompressed BMP file format, GIF uses lossless compression and supports animation without audio. Graphics Interchange Format (GIF) is a type of bitmap file format that relies on pixels to form simple images using the RGB color model. ![]() ![]() ![]() 2 n = 22*.Ī relict species of the Cretaceous and Cenozoic, when this genus was widely distributed in what is now NE China, Europe, Greenland, Japan, North America, and Russia (Siberia). Seeds 5-9, compressed-obovoid, winged all round, apex emarginate. Seed cones terminal or subterminal on previous year’s growth, solitary, shortly pedunculate at pollination, becoming long pedunculate and pendulous, subglobose, slightly cubic, or occasionally oblong-globose, ripening in 1st year peduncle clothed with decussate, linear leaves cone scales 16-24, persistent, decussate, shieldlike, woody, grooved, 5-9-seeded (when fertile), base cuneate, distal part transversely rhombic. Delicate filigree leaves remain gold throughout the summer ending in an autumn display of. Pollen cones developing in autumn but not shedding pollen until following spring, borne in spikes or panicles, shortly pedunculate microsporophylls 15-20, decussate, each with 3 pollen sacs, except apical and basal with 2. Leaves deciduous together with lateral branchlet as a unit, decussate, 2-ranked, spirally arranged on leading branchlets, ± sessile blade linear, flattened, soft, midvein depressed adaxially, raised abaxially, stomatal bands 4-8, on abaxial surface only, or on both surfaces on seedling leaves, base twisted. 4 whorls of early deciduous, salmon-colored basal scales. Trees deciduous, monoecious main branches irregularly whorled branchlets of several kinds: persistent or deciduous, opposite or subopposite, developing from paired, superimposed axillary buds, 1 of which remains dormant as a winter bud winter buds ovoid or ellipsoid, with 6-8 pairs of decussate, ovate, membranous, scales branchlets each subtended by ca. The species are cultivated in the parks, gardens, and roadsides in many countries. It will resolve the differences of each software.8. Cheng is one of the oldest living conifer species, and it has remained unchanged for millions of years compared to its fossils from the Cretaceous period. When you import or export, Metasequoia will support the conversion of the coordinate axes, and reversing the surface direction, and specifying the magnification factor. You can pass files to each other with most of software. Metasequoia supports several file formats of third-party 3DCG and 3DCAD software. (*In Standard Edition, there is an upper limit to the rendering resolution.) Import / Export (*Separately, the installation of RenderMan(Commercial or non-commercial) is required.) It works with Pixar's renderer "RenderMan" to provide more accurate rendering than the built-in renderer. This feature will reduce the time to create the object.Īnd you can edit the generated object in more detail by modeling capabilities. You can create an object by specifying only the center line and the line width. Armatureīy, you can create an object shape along the center line. And you can easily add edges (divide a face) or erase edges (merge faces). ![]() ![]() N-gon (5 or more points in a face) You can make a polygon with 5 or more points. Bevel - creating a fillet surface (a rounded corner) is added.Bridge - It creates a pipe-shaped polygon in between holes.Fill up a hole - It automatically fills in the holes on the surface.The following features have been added and improved, in ver.4.0 or later. And it also has functions to assist in the finer processing. Metasequoia has basic polygon editing functions. Buttons and icons are displayed beautifully, in high resolution monitors (like as IGZO or Retina display). You can use it in much the same way on different platforms.Īll GUI components are displayed by vector drawings. Metasequoia 4 is the 3DCG modeling software for Windows or macOS. ![]() ![]() However, the developers recommend a CPU greater or equal to an Intel Core i5-8400 to play the game. To play F18 Carrier Landing you will need a minimum CPU equivalent to an Intel Core i5-4590. ![]() In terms of game file size, you will need at least 6 GB of free disk space available. Furthermore, an NVIDIA GeForce GTX 1060 is recommended in order to run F18 Carrier Landing with the highest settings. Choose from all white or all black gaming desks or a mix of the two.Provided that you have at least an NVIDIA GeForce GTX 970 graphics card you can play the game. Need more smart design elements to fill out your gaming rig? Easily move CPU towers out of the way with CPU stands on casters, get a stylish accessories stand for your headphones or find multi-functional cushion/blankets and gaming mouse pads featuring slick designs.Īll gaming desks feature sustainable, durable and sturdy materials such as strong and light-weight fiberboard and powder coated steel. Add even more customizable comfort to touch-of-a-button adjustable desks by pairing with IKEA gaming chairs built for sport that were also designed in collaboration with ROG. Meanwhile, for added convenience, choose gaming desks with a USB port built-in to the controller of adjustable height desks that allow you to charge one device. Cable management is even easier with gaming desks with a cable management tray under the tabletop that will keep your desk neat and tidy. To add further customization, most gaming desks can be positioned in one of two ways: with the contour of the desk facing forward to provide relief for your forearms and wrists, or having the contour at the back to create a tidy gap for cables to cascade downward from. ![]() Find gaming desks that further reduce eye strain with a durable matte surface that cuts down on reflective glare. To help prevent eye strain, choose a gaming desk with a deep tabletop that allows you to position screens at a comfortable distance from the eyes. Enjoy built-in comfort that gives you an edge when matches drag on. The true measure of a gaming desk isn’t just how it feels when you first sit down-it’s how it helps you game longer. Whether adjustable in height or not, there are gaming desks in a wide range of sizes-from a minimum height of 29 ½” to as high as 57 ½” (with shelving).Ĭhoose wide and deep desks with enough room to easily accommodate everything you need to game, from multiple gaming monitors to cams, keyboards, and mouse pads, as well as your speakers and headphones. Or choose desks with legs whose height can be adjusted manually from 27 to 30”. Consider preset “sweet spots” your comfort zones for different types of gaming that can keep you playing longer. Find gaming desks with electronically adjustable height that can be adjusted from 29 to 47” or pre-set to four different height positions that you can easily change to. Taking your game to the next level is easy with loads of smart design features, including adjustable push-of-a-button height that allows you to always sit or stand at exactly where you want to be. ![]() Put a gaming desk made in collaboration with Republic of Gamers (ROG) at the centerpiece of your gaming setup. Enjoy features tailored to your specific gaming needs that maximizes space while keeping you comfortable and going strong through marathon gaming sessions. ![]() Raise your game with gaming desks as customizable as any game mod. ![]() ![]() ![]() Often the thinning becomes so profound that a full-thickness hole atrophies through the retina at the lattice lesion. The retinal thinning has several effects: (1) the overlying vitreous will be disturbed, resulting in a pocket of liquefaction overlying the lattice lesion known as a lacuna (2) the vitreous along the edges of the lattice lesion will undergo strong adhesion to the retina and (3) the ischemia and retinal thinning will disturb the retinal pigment epithelium, resulting in RPE hyperplasia and a pigmented appearance. There is sclerosis of the larger vessels, with their lumen being filled with extracellular glial tissue, giving lattice degeneration its characteristic fibrotic appearance. It appears to be due to dropout of peripheral retinal capillaries with resulting ischemia, which induces thinning of all retinal layers. Lattice degeneration is typically bilateral. A tractional linear tear will occur on the posterior edge of lattice lesions in 1.9 percent of lesions. The incidence of atrophic holes in lattice degeneration ranges from 18 to 42 percent. Atrophic holes are often present in the lesion, occasionally large enough to encompass the entire lattice lesion. There may be associated RPE hyperplasia, giving the lesion a pigmented appearance. The individual lesions are usually from one-half to six disc diameters and may run 360 degrees around the eye in a discontinuous pattern. It nearly always runs circumferentially between the equator and the ora serrata. It presents as a linear trail of fibrosed vessels within atrophied retina in a "lattice" pattern. Lattice degeneration occurs in eight to 11 percent of the general population. There is no racial or sexual predilection. There appears to be a higher incidence of myopia in patients with lattice degeneration. Mutations in COL111A2 can give rise to a syndrome with the systemic features of Stickler syndrome but no ophthalmological abnormality.The patient is usually over age 20 and is nearly always asymptomatic, except for possible complaints of flashing lights (photopsia). The remainder with the type 2 vitreous phenotype have mutations in COL11A1 or other loci yet to be identified. The majority of families with Stickler syndrome have mutations in the COL2A1 gene and show the characteristic type 1 vitreous phenotype. Mitral valve prolapse was reported to be a common finding in one series but not in our experience. Stature and intellect are usually normal. Occasional findings include slender extremities and long fingers. Sensorineural deafness with high tone loss may be asymptomatic or mild. Mild spondyloepiphyseal dysplasia is often apparent radiologically. Osteoarthritis develops typically in the third or fourth decade. There is joint hypermobility which declines with age. Midline clefting, if present, ranges in severity from a cleft of the soft palate to Pierre-Robin sequence. These features can become less pronounced with age. Children with Stickler syndrome typically have a flat midface with depressed nasal bridge, short nose, anteverted nares, and micrognathia. Non-ocular features show great variation in expression. Less common ophthalmological features include paravascular pigmented lattice degeneration and cataracts. There is a substantial risk of retinal detachment. Abnormalities of vitreous gel architecture are a pathognomonic feature, usually associated with high myopia which is congenital and non-progressive. Stickler syndrome is an autosomal dominant disorder with characteristic ophthalmological and orofacial features, deafness, and arthritis. ![]() |